when you may get 10065 WSA E host unreach?

This is mainly because of Firewall on your computer

and we may see this message
C:\Documents and Settings\suresh>pdestate -a
PDE state is RUN/STARTED.
DBS state is 7: System is operational without PEs - Sessions are not allowed

After turning off firewall, if you are still having issue then we may to
bring PE to ONLINE using MULTITOOL.
Once logon to Multitool you may see the following things:

Then we need to set PE state using Tools --> Vproc Manager

Then Vproc Manager opens. then select tab Set Vproc State.


Then set offline PE to online... Now we see





C:\Documents and Settings\suresh>pdestate -a
PDE state is RUN/STARTED.
DBS state is 4: Logons are enabled - Users are logged on